Effect of streptozotocin induced diabetes on rat hippocampus

Hypoglycemic effect of Polygonatum orientale Desf. rhizome extract on diabetes induced by streptozotocin in rat model

Background: Polygonatum orientale, an herbaceous and perennial plant from family Asparagaceae, is native to the forests of northern Iran. The hypoglycemic effects of other species of the Polygonatum have been proven. Objective: The aim of this study was to evaluate the hypoglycemic effect of P. orientale rhizome extract and its effects on the antioxidant enzymes in the plasma of the normal and ...

Effect of environmental enrichment exposure on neuronal morphology of streptozotocin-induced diabetic and stressed rat hippocampus.

BACKGROUND Environmental enrichment (EE) exposure is known to influence the structural changes in the neuronal network of hippocampus. In the present study, we evaluated the effects of EE exposure on the streptozotocin (STZ)-induced diabetic and stressed rat hippocampus. METHODS Male albino rats of Wistar strain (4-5 weeks old) were grouped into normal control (NC), vehicle control (VC), diab...

the effect of aqueous extract of garlic on formalin-induced pain in male rats

چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...

Effects of Melissa Officinalis Extract on Streptozotocin-Induced Diabetes in Rat Models; a Stereological Study

Background and objectives: Melissa officinalis (MO) has shown antioxidant and anti-inflammatory properties and is traditionally believed to have anti-hyperglycemic effects. This study aims to evaluate the protective effects of MO on streptozotocin (STZ) induced pancreatic damage and thereupon diabetes in rats. Methods: STZ (60 mg/kg) was injected intraperitoneally to the rats in order to induc...

effect of exercise on diabetes-induced oxidative stress in the rat hippocampus